8BK0
Crystal structure of human Ephrin type-A receptor 2 (EPHA2) Kinase domain in complex with LDN-211904
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ephrin type-A receptor 2 | polymer | 306 | 34462.8 | 1 | UniProt (P29317) Pfam (PF07714) In PDB | Homo sapiens (human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
3 | A | ~{N}-(2-chlorophenyl)-6-piperidin-4-yl-imidazo[1,2-a]pyridine-3-carboxamide | non-polymer | 354.8 | 1 | Chemie (QJI) | |||
4 | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence modifications
A: 596 - 900 (UniProt: P29317)
PDB | External Database | Details |
---|---|---|
Gly 595 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34462.8 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 851.4 | |
All* | Total formula weight | 35314.2 |