8BJU
HUMAN WEE1 KINASE IN COMPLEX WITH INHIBITOR 1-[6-(1-Hydroxy-1-methyl-ethyl)-pyridin-2-yl]-2-(2-methoxy-phenyl)-6-[4-(4-methyl-piperazin-1-yl)-phenylamino]-1,2-dihydro-pyrazolo[3,4-d]pyrimidin-3-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Wee1-like protein kinase | polymer | 285 | 32168.6 | 1 | UniProt (P30291) Pfam (PF00069) | Homo sapiens (human) | WEE1hu,Wee1A kinase |
| 2 | B (A) | 2-(2-methoxyphenyl)-6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1-[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]pyrazolo[3,4-d]pyrimidin-3-one | non-polymer | 566.7 | 1 | Chemie (QT9) | |||
| 3 | C (A) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32168.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 566.7 | |
| All* | Total formula weight | 32735.3 |
