8BIO
Crystal structure of human Ephrin type-A receptor 2 (EPHA2) Kinase domain in complex with MRAL5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ephrin type-A receptor 2 | polymer | 306 | 34462.8 | 1 | UniProt (P29317) Pfam (PF07714) | Homo sapiens (human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
| 2 | B, C, D, E, F... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 13 | Chemie (EDO) | |||
| 3 | M (A) | 8-(4-azanylbutyl)-6-[2-chloranyl-5-(trifluoromethyl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | non-polymer | 425.8 | 1 | Chemie (QRD) | |||
| 4 | P (A) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
A: 596 - 900 (UniProt: P29317)
| PDB | External Database | Details |
|---|---|---|
| Gly 595 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34462.8 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1232.7 | |
| All* | Total formula weight | 35695.6 |
