8BHY
DNA-PK Ku80 mediated dimer bound to PAXX and XLF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, S | DNA-dependent protein kinase catalytic subunit | polymer | 4128 | 469673.2 | 2 | UniProt (P78527) Pfam (PF20502) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260) In PDB | Homo sapiens (human) | DNA-PK catalytic subunit,DNA-PKcs,DNPK1,p460 |
| 2 | B, T | X-ray repair cross-complementing protein 6 | polymer | 609 | 69945.0 | 2 | UniProt (P12956) Pfam (PF02037) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) In PDB | Homo sapiens (human) | 5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6 |
| 3 | C, L | X-ray repair cross-complementing protein 5 | polymer | 732 | 82812.4 | 2 | UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF08785) In PDB | Homo sapiens (human) | 86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 4 | D, M | Protein PAXX | polymer | 204 | 21663.5 | 2 | UniProt (Q9BUH6) Pfam (PF15384) In PDB | Homo sapiens (human) | Paralog of XRCC4 and XLF,XRCC4-like small protein |
| 5 | G, H, P, Q | DNA repair protein XRCC4 | polymer | 336 | 38337.7 | 4 | UniProt (Q13426) Pfam (PF06632) In PDB | Homo sapiens (human) | X-ray repair cross-complementing protein 4 |
| 6 | I, R | DNA ligase 4 | polymer | 911 | 104125.0 | 2 | UniProt (P49917) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) Pfam (PF00533) Pfam (PF11411) In PDB | Homo sapiens (human) | DNA ligase IV,Polydeoxyribonucleotide synthase [ATP] 4 |
| 7 | d | DNA (25-MER) | polymer | 25 | 7733.0 | 1 | Homo sapiens | ||
| 8 | e | DNA (27-MER) | polymer | 27 | 8290.4 | 1 | Homo sapiens | ||
| 9 | i | DNA (26-MER) | polymer | 26 | 7961.2 | 1 | Homo sapiens | ||
| 10 | j | DNA (5'-D(P*AP*AP*TP*AP*AP*TP*AP*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*G)-3') | polymer | 24 | 7443.8 | 1 | Homo sapiens | ||
| 11 | f, m | Non-homologous end-joining factor 1 | polymer | 299 | 33372.2 | 2 | UniProt (Q9H9Q4) Pfam (PF09302) In PDB | Homo sapiens (human) | Protein cernunnos,XRCC4-like factor |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 1747962.1 | |
| All* | Total formula weight | 1747962.1 |
