8BG0

Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains | ABeta40

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (D, A, B, C)	Amyloid-beta precursor protein	polymer	40	4263.8	4	UniProt (P05067) Pfam (PF03494)	Homo sapiens (human)	APP,ABPP,APPI,Alzheimer disease amyloid protein,Amyloid precursor protein,Amyloid-beta A4 protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II
2	E, F, G (D, B, C)	water	water		18.0	12	Chemie (HOH)

Sequence modifications

D, A, B, C: 1 - 40 (UniProt: P05067)

PDB	External Database	Details
Gly 22	Glu 637	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	17055.2
All*	Total formula weight	17055.2

*Water molecules are not included.