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8BFU

Crystal structure of the apo p110alpha catalytic subunit from homo sapiens

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformpolymer946109983.11UniProt (P42336)
Pfam (PF00794)
Pfam (PF00792)
Pfam (PF00613)
Pfam (PF00454)
Homo sapiens (human)PI3-kinase subunit alpha,PI3K-alpha,PI3Kalpha,PtdIns-3-kinase subunit alpha,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,PtdIns-3-kinase subunit p110-alpha,p110alpha,Phosphoinositide 3-kinase alpha,Phosphoinositide-3-kinase catalytic alpha polypeptide,Serine/threonine protein kinase PIK3CA
2B
(A)
waterwater18.051Chemie (HOH)
Sequence modifications
A: 105 - 1048 (UniProt: P42336)
PDBExternal DatabaseDetails
Gly 103-expression tag
Ser 104-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight109983.1
All*Total formula weight109983.1
*Water molecules are not included.

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PDB entries from 2024-11-06

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