8BFI

human CNOT1-CNOT10-CNOT11 module

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CCR4-NOT transcription complex subunit 1	polymer	778	88423.8	1	UniProt (A5YKK6) Pfam (PF22940) Pfam (PF16418)	Homo sapiens (human)	CCR4-associated factor 1,Negative regulator of transcription subunit 1 homolog,NOT1H,hNOT1
2	B (B)	CCR4-NOT transcription complex subunit 10	polymer	718	79251.7	1	UniProt (Q9H9A5)	Homo sapiens (human)
3	C (C)	CCR4-NOT transcription complex subunit 11	polymer	455	50624.2	1	UniProt (Q9UKZ1) Pfam (PF10155)	Homo sapiens (human)

Sequence modifications

A: 1 - 687 (UniProt: A5YKK6)

PDB	External Database	Details
Mse -90	-	initiating methionine
His -89	-	expression tag
His -88	-	expression tag
His -87	-	expression tag
His -86	-	expression tag
His -85	-	expression tag
His -84	-	expression tag
Gly -83	-	expression tag
Mse -82	-	expression tag
Glu -81	-	expression tag
Gly -80	-	expression tag
Glu -79	-	expression tag
Tyr -78	-	expression tag
Ile -77	-	expression tag
Lys -76	-	expression tag
Leu -75	-	expression tag
Lys -74	-	expression tag
Val -73	-	expression tag
Ile -72	-	expression tag
Gly -71	-	expression tag
Gln -70	-	expression tag
Asp -69	-	expression tag
Ser -68	-	expression tag
Ser -67	-	expression tag
Glu -66	-	expression tag
Ile -65	-	expression tag
His -64	-	expression tag
Phe -63	-	expression tag
Lys -62	-	expression tag
Val -61	-	expression tag
Lys -60	-	expression tag
Mse -59	-	expression tag
Thr -58	-	expression tag
Thr -57	-	expression tag
His -56	-	expression tag
Leu -55	-	expression tag
Lys -54	-	expression tag
Lys -53	-	expression tag
Leu -52	-	expression tag
Lys -51	-	expression tag
Glu -50	-	expression tag
Ser -49	-	expression tag
Tyr -48	-	expression tag
Cys -47	-	expression tag
Gln -46	-	expression tag
Arg -45	-	expression tag
Gln -44	-	expression tag
Gly -43	-	expression tag
Val -42	-	expression tag
Pro -41	-	expression tag
Mse -40	-	expression tag
Asn -39	-	expression tag
Ser -38	-	expression tag
Leu -37	-	expression tag
Arg -36	-	expression tag
Phe -35	-	expression tag
Leu -34	-	expression tag
Phe -33	-	expression tag
Glu -32	-	expression tag
Gly -31	-	expression tag
Gln -30	-	expression tag
Arg -29	-	expression tag
Ile -28	-	expression tag
Ala -27	-	expression tag
Asp -26	-	expression tag
Asn -25	-	expression tag
His -24	-	expression tag
Thr -23	-	expression tag
Pro -22	-	expression tag
Lys -21	-	expression tag
Glu -20	-	expression tag
Leu -19	-	expression tag
Gly -18	-	expression tag
Mse -17	-	expression tag
Glu -16	-	expression tag
Glu -15	-	expression tag
Glu -14	-	expression tag
Asp -13	-	expression tag
Val -12	-	expression tag
Ile -11	-	expression tag
Glu -10	-	expression tag
Val -9	-	expression tag
Tyr -8	-	expression tag
Gln -7	-	expression tag
Glu -6	-	expression tag
Gln -5	-	expression tag
Thr -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
Ser 0	-	expression tag
Val 381	Ile 381	conflict
Val 649	Ala 649	conflict
Thr 681	Met 681	conflict

B: 1 - 714 (UniProt: Q9H9A5)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
Asp -1	-	expression tag
Ser 0	-	expression tag

C: 61 - 510 (UniProt: Q9UKZ1)

PDB	External Database	Details
Gly 56	-	expression tag
Pro 57	-	expression tag
Asp 58	-	expression tag
Arg 59	-	expression tag
Ser 60	-	expression tag
Glu 507	Lys 507	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	218299.6
All*	Total formula weight	218299.6

*Water molecules are not included.