8BF2
Human PPARgamma in complex with MEHP bound to the AF-2 and omega sub-pockets
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peroxisome proliferator-activated receptor gamma | polymer | 283 | 32412.6 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
2 | A, B | 2-[(2~{S})-2-ethylhexoxy]carbonylbenzoic acid | non-polymer | 278.3 | 3 | Chemie (QGL) | |||
3 | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A, B: 206 - 477 (UniProt: P37231)
PDB | External Database | Details |
---|---|---|
Met 195 | - | initiating methionine |
Arg 196 | - | expression tag |
Gly 197 | - | expression tag |
Ser 198 | - | expression tag |
His 199 | - | expression tag |
His 200 | - | expression tag |
His 201 | - | expression tag |
His 202 | - | expression tag |
His 203 | - | expression tag |
His 204 | - | expression tag |
Gly 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 64825.2 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 835.0 | |
All* | Total formula weight | 65660.2 |