8BC1

Cryo-EM Structure of Ca2+-bound mTMEM16F F518A_Q623A mutant in GDN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Anoctamin-6,mTMEM16F	polymer	975	113330.5	2	UniProt (Q6P9J9) Pfam (PF16178) Pfam (PF04547) In PDB	Mus musculus (house mouse)	Small-conductance calcium-activated nonselective cation channel,SCAN channel,Transmembrane protein 16F
2	A, B	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)

Sequence modifications

A, B: 1 - 911 (UniProt: Q6P9J9)

PDB	External Database	Details
Ala 518	Phe 518	engineered mutation
Ala 623	Gln 623	engineered mutation

A, B: 912 - 975 (PDB: 8BC1)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	226661.0
Non-Polymers*	Number of molecules	6
	Total formula weight	240.5
All*	Total formula weight	226901.4

*Water molecules are not included.