8BAV

Secretagogin (human) in complex with its target peptide from SNAP-25

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Green fluorescent protein,Synaptosomal-associated protein 25	polymer	258	28980.6	2	UniProt (P42212) UniProt (P60880) Pfam (PF01353) In PDB	Aequorea victoria	SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein
2	C, D	Secretagogin	polymer	276	32085.8	2	UniProt (O76038) Pfam (PF00036) Pfam (PF13202) In PDB	Homo sapiens (human)
3	A, B	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4	C, D	CALCIUM ION	non-polymer		40.1	8	Chemie (CA)
5	D	TRIS-HYDROXYMETHYL-METHYL-AMMONIUM	non-polymer		122.1	1	Chemie (144)
6		water	water		18.0	422	Chemie (HOH)

Sequence modifications

A, B: 2 - 228 (UniProt: P42212)

PDB	External Database	Details
Ser -1	-	expression tag
Met 0	-	expression tag
Ala 1	-	expression tag
Leu 64	Phe 64	engineered mutation
Cro 66	Ser 65	chromophore
Cro 66	Tyr 66	chromophore
Cro 66	Gly 67	chromophore
Arg 80	Gln 80	engineered mutation
Thr 167	Ile 167	engineered mutation
Thr 229	-	linker
Met 230	-	linker
Ala 231	-	linker

A, B: 232 - 256 (UniProt: P60880)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	122132.8
Non-Polymers*	Number of molecules	11
	Total formula weight	560.9
All*	Total formula weight	122693.7

*Water molecules are not included.