8BAC
Crystal structure of human heparanase in complex with competitive inhibitor GD05
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA | Heparanase 50 kDa subunit | polymer | 389 | 43733.3 | 1 | UniProt (Q9Y251) Pfam (PF03662) In PDB | Homo sapiens (human) | |
2 | BBB | Heparanase 8 kDa subunit | polymer | 74 | 8273.5 | 1 | UniProt (Q9Y251) In PDB | Homo sapiens (human) | |
3 | AAA | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
4 | AAA | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
5 | AAA | (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid | non-polymer | 161.2 | 1 | Chemie (SJ5) | |||
6 | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
AAA: 158 - 543 (UniProt: Q9Y251)
PDB | External Database | Details |
---|---|---|
Asp 155 | - | expression tag |
Pro 156 | - | expression tag |
Gly 157 | - | expression tag |
Arg 307 | Lys 307 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 52006.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 665.6 | |
All* | Total formula weight | 52672.5 |