8BAC
Crystal structure of human heparanase in complex with competitive inhibitor GD05
This is a non-PDB format compatible entry.
Functional Information from GO Data
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E97, ECO:0007744|PDB:5E98, ECO:0007744|PDB:5E9B, ECO:0007744|PDB:5E9C |
Chain | Residue | Details |
BBB | ASP27 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E97, ECO:0007744|PDB:5E98, ECO:0007744|PDB:5E9B |
Chain | Residue | Details |
BBB | THR62 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:15760902 |
Chain | Residue | Details |
AAA | LYS158 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:15760902, ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E9C |
Chain | Residue | Details |
AAA | GLN270 |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E9C |
Chain | Residue | Details |
AAA | HIS296 | |
AAA | ARG303 |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E97, ECO:0007744|PDB:5E98, ECO:0007744|PDB:5E9B |
Chain | Residue | Details |
AAA | TYR348 | |
AAA | GLY389 |
site_id | SWS_FT_FI7 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14573609, ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E8M, ECO:0007744|PDB:5E97 |
Chain | Residue | Details |
AAA | ASN162 |
site_id | SWS_FT_FI8 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14573609 |
Chain | Residue | Details |
AAA | ASN178 |
site_id | SWS_FT_FI9 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14573609, ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E8M, ECO:0007744|PDB:5E97, ECO:0007744|PDB:5E98, ECO:0007744|PDB:5E9B, ECO:0007744|PDB:5E9C |
Chain | Residue | Details |
AAA | ASN200 | |
AAA | ASN459 |
site_id | SWS_FT_FI10 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14573609, ECO:0000269|PubMed:16263699, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E8M |
Chain | Residue | Details |
AAA | ASN217 |
site_id | SWS_FT_FI11 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14573609, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E8M, ECO:0007744|PDB:5E97, ECO:0007744|PDB:5E98, ECO:0007744|PDB:5E9B, ECO:0007744|PDB:5E9C |
Chain | Residue | Details |
AAA | ASN238 |