8B9N
Crystal structure of NEI domain of mouse NEIL3 trapped in covalent complex with ssDNA with abasic site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Endonuclease 8-like 3 | polymer | 290 | 32089.2 | 2 | UniProt (Q8K203) Pfam (PF06831) | Mus musculus (house mouse) | DNA glycosylase FPG2,DNA glycosylase/AP lyase Neil3,Endonuclease VIII-like 3,Nei-like protein 3 |
| 2 | B, D (B, D) | ssDNA with abasic site | polymer | 12 | 3505.3 | 2 | Mus musculus | ||
| 3 | E, F (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 282 (UniProt: Q8K203)
| PDB | External Database | Details |
|---|---|---|
| Pro 46 | Leu 46 | conflict |
| His 90 | Pro 90 | conflict |
| Gly 114 | Ala 114 | conflict |
| Glu 150 | Val 150 | conflict |
| Arg 220 | Cys 220 | conflict |
| Gly 256 | Asp 256 | conflict |
| Asp 283 | - | expression tag |
| Gly 284 | - | expression tag |
| Leu 285 | - | expression tag |
| Glu 286 | - | expression tag |
| Val 287 | - | expression tag |
| Leu 288 | - | expression tag |
| Phe 289 | - | expression tag |
| Gln 290 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71188.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 71319.7 |
