Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (2) | DNA replication licensing factor MCM2 | polymer | 904 | 102034.1 | 1 | UniProt (P49736) Pfam (PF12619) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Homo sapiens (human) | Minichromosome maintenance protein 2 homolog,Nuclear protein BM28 |
| 2 | B (3) | DNA replication licensing factor MCM3 | polymer | 808 | 91110.9 | 1 | UniProt (P25205) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Homo sapiens (human) | DNA polymerase alpha holoenzyme-associated protein P1,P1-MCM3,RLF subunit beta,p102 |
| 3 | C (4) | DNA replication licensing factor MCM4 | polymer | 863 | 96684.9 | 1 | UniProt (P33991) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Homo sapiens (human) | CDC21 homolog,P1-CDC21 |
| 4 | D (5) | DNA replication licensing factor MCM5 | polymer | 734 | 82406.6 | 1 | UniProt (P33992) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21933) | Homo sapiens (human) | CDC46 homolog,P1-CDC46 |
| 5 | E (6) | DNA replication licensing factor MCM6 | polymer | 821 | 93010.3 | 1 | UniProt (Q14566) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF18263) | Homo sapiens (human) | p105MCM |
| 6 | F (7) | DNA replication licensing factor MCM7 | polymer | 719 | 81411.9 | 1 | UniProt (P33993) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Homo sapiens (human) | CDC47 homolog,P1.1-MCM3 |
| 7 | G (A) | DNA polymerase alpha subunit B | polymer | 598 | 66015.5 | 1 | UniProt (Q14181) Pfam (PF08418) Pfam (PF22062) Pfam (PF04042) | Homo sapiens (human) | DNA polymerase alpha 70 kDa subunit |
| 8 | H (C) | Cell division control protein 45 homolog | polymer | 569 | 66016.9 | 1 | UniProt (O75419) Pfam (PF02724) | Homo sapiens (human) | PORC-PI-1 |
| 9 | I (D) | DNA replication complex GINS protein PSF1 | polymer | 196 | 23022.5 | 1 | UniProt (Q14691) Pfam (PF05916) | Homo sapiens (human) | GINS complex subunit 1 |
| 10 | J (E) | DNA replication complex GINS protein PSF2 | polymer | 185 | 21453.7 | 1 | UniProt (Q9Y248) Pfam (PF05916) | Homo sapiens (human) | GINS complex subunit 2 |
| 11 | K (F) | DNA replication complex GINS protein PSF3 | polymer | 216 | 24562.6 | 1 | UniProt (Q9BRX5) Pfam (PF22466) Pfam (PF05916) | Homo sapiens (human) | GINS complex subunit 3 |
| 12 | L (G) | DNA replication complex GINS protein SLD5 | polymer | 261 | 29983.0 | 1 | UniProt (Q9BRT9) Pfam (PF05916) Pfam (PF16922) | Homo sapiens (human) | GINS complex subunit 4 |
| 13 | M (K) | Protein timeless homolog | polymer | 1209 | 138903.0 | 1 | UniProt (Q9UNS1) Pfam (PF04821) Pfam (PF05029) | Homo sapiens (human) | hTIM |
| 14 | N (L) | TIMELESS-interacting protein | polymer | 301 | 34600.2 | 1 | UniProt (Q9BVW5) Pfam (PF07962) | Homo sapiens (human) | |
| 15 | O (M) | Leading strand DNA | polymer | 84 | 26092.6 | 1 | Homo sapiens | ||
| 16 | P (N) | DNA Molecule | polymer | 86 | 26402.9 | 1 | Homo sapiens | ||
| 17 | Q (P) | DNA primase large subunit | polymer | 509 | 58890.9 | 1 | UniProt (P49643) Pfam (PF04104) | Homo sapiens (human) | DNA primase 58 kDa subunit,p58 |
| 18 | R (Q) | Claspin | polymer | 1371 | 155184.7 | 1 | UniProt (Q9HAW4) | Homo sapiens (human) | hClaspin |
| 19 | S (O) | DNA primase small subunit | polymer | 462 | 54242.6 | 1 | UniProt (P49642) Pfam (PF01896) | Homo sapiens (human) | DNA primase 49 kDa subunit,p49 |
| 20 | T, V, W (H, J, I) | WD repeat and HMG-box DNA-binding protein 1 | polymer | 1160 | 129967.0 | 3 | UniProt (O75717) Pfam (PF00400) Pfam (PF12894) Pfam (PF12341) Pfam (PF20946) | Homo sapiens (human) | Acidic nucleoplasmic DNA-binding protein 1,And-1 |
| 21 | U (B) | DNA polymerase alpha catalytic subunit | polymer | 1504 | 170392.7 | 1 | UniProt (P09884) Pfam (PF12254) Pfam (PF03104) Pfam (PF00136) Pfam (PF08996) | Homo sapiens (human) | DNA polymerase alpha catalytic subunit p180 |
| 22 | DA, X, Z (5, 2, 3) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 3 | Chemie (ANP) | |||
| 23 | AA, EA, Y (3, 5, 2) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 24 | BA, CA, FA, GA (4, 5, 6, 7) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
C: 1 - 134 (UniProt: O75419)
C: 135 - 566 (UniProt: O75419)
G: 1 - 223 (UniProt: Q9BRT9)
K: 1 - 1208 (UniProt: Q9UNS1)
Q: 1 - 1339 (UniProt: Q9HAW4)
O: 1 - 420 (UniProt: P49642)
H, J, I: 1 - 1129 (UniProt: O75717)
B: 1 - 1462 (UniProt: P09884)
C: 135 - 566 (UniProt: O75419)
| PDB | External Database | Details |
|---|---|---|
| Asp 135 | - | linker |
| Tyr 135 | - | linker |
| Lys 135 | - | linker |
| Asp 135 | - | linker |
| Asp 135 | - | linker |
| Asp 135 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Trp -37 | - | expression tag |
| Ser -36 | - | expression tag |
| His -35 | - | expression tag |
| Pro -34 | - | expression tag |
| Gln -33 | - | expression tag |
| Phe -32 | - | expression tag |
| Glu -31 | - | expression tag |
| Lys -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Gly -28 | - | expression tag |
| Gly -27 | - | expression tag |
| Ser -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Ser -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Ser -19 | - | expression tag |
| Ala -18 | - | expression tag |
| Trp -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| Pro -14 | - | expression tag |
| Gln -13 | - | expression tag |
| Phe -12 | - | expression tag |
| Glu -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 1340 | - | expression tag |
| Glu 1341 | - | expression tag |
| Val 1342 | - | expression tag |
| Leu 1343 | - | expression tag |
| Phe 1344 | - | expression tag |
| Gln 1345 | - | expression tag |
| Gly 1346 | - | expression tag |
| Pro 1347 | - | expression tag |
| Asp 1348 | - | expression tag |
| Tyr 1349 | - | expression tag |
| Lys 1350 | - | expression tag |
| Asp 1351 | - | expression tag |
| Asp 1352 | - | expression tag |
| Asp 1353 | - | expression tag |
| Asp 1354 | - | expression tag |
| Lys 1355 | - | expression tag |
| Asp 1356 | - | expression tag |
| Tyr 1357 | - | expression tag |
| Lys 1358 | - | expression tag |
| Asp 1359 | - | expression tag |
| Asp 1360 | - | expression tag |
| Asp 1361 | - | expression tag |
| Asp 1362 | - | expression tag |
| Lys 1363 | - | expression tag |
| Asp 1364 | - | expression tag |
| Tyr 1365 | - | expression tag |
| Lys 1366 | - | expression tag |
| Asp 1367 | - | expression tag |
| Asp 1368 | - | expression tag |
| Asp 1369 | - | expression tag |
| Asp 1370 | - | expression tag |
| Lys 1371 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -41 | - | initiating methionine |
| Ala -40 | - | expression tag |
| Ser -39 | - | expression tag |
| Ala -38 | - | expression tag |
| Trp -37 | - | expression tag |
| Ser -36 | - | expression tag |
| His -35 | - | expression tag |
| Pro -34 | - | expression tag |
| Gln -33 | - | expression tag |
| Phe -32 | - | expression tag |
| Glu -31 | - | expression tag |
| Lys -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Gly -28 | - | expression tag |
| Gly -27 | - | expression tag |
| Ser -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Ser -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Ser -19 | - | expression tag |
| Ala -18 | - | expression tag |
| Trp -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| Pro -14 | - | expression tag |
| Gln -13 | - | expression tag |
| Phe -12 | - | expression tag |
| Glu -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp -30 | - | expression tag |
| Tyr -29 | - | expression tag |
| Lys -28 | - | expression tag |
| Asp -27 | - | expression tag |
| Asp -26 | - | expression tag |
| Asp -25 | - | expression tag |
| Asp -24 | - | expression tag |
| Lys -23 | - | expression tag |
| Asp -22 | - | expression tag |
| Tyr -21 | - | expression tag |
| Lys -20 | - | expression tag |
| Asp -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Asp -16 | - | expression tag |
| Lys -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Tyr -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -41 | - | initiating methionine |
| Ala -40 | - | expression tag |
| Ser -39 | - | expression tag |
| Ala -38 | - | expression tag |
| Trp -37 | - | expression tag |
| Ser -36 | - | expression tag |
| His -35 | - | expression tag |
| Pro -34 | - | expression tag |
| Gln -33 | - | expression tag |
| Phe -32 | - | expression tag |
| Glu -31 | - | expression tag |
| Lys -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Gly -28 | - | expression tag |
| Gly -27 | - | expression tag |
| Ser -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Ser -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Ser -19 | - | expression tag |
| Ala -18 | - | expression tag |
| Trp -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| Pro -14 | - | expression tag |
| Gln -13 | - | expression tag |
| Phe -12 | - | expression tag |
| Glu -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 23 |
| Total formula weight | 1832323.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1853.1 | |
| All* | Total formula weight | 1834176.5 |
