8B5B
Human BRD4 bromdomain 1 in complex with a H4 peptide containing acetyl lysine and ApmTri (H4K5acK8ApmTri)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Bromodomain-containing protein 4 | polymer | 129 | 15294.6 | 3 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (human) | Protein HUNK1 |
| 2 | D, E (D, E) | H4K5acK8ApmTri | polymer | 13 | 1237.4 | 2 | UniProt (by SIFTS) (P62805) | Homo sapiens | |
| 3 | F (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | G, H, I, J, K (A, B, C, D, E) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A, B, C: 44 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Gly 40 | - | expression tag |
| Ser 41 | - | expression tag |
| His 42 | - | expression tag |
| Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 48358.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 106.1 | |
| All* | Total formula weight | 48464.7 |
