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8B5B

Human BRD4 bromdomain 1 in complex with a H4 peptide containing acetyl lysine and ApmTri (H4K5acK8ApmTri)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CBromodomain-containing protein 4polymer12915294.63UniProt (O60885)
Pfam (PF00439)
In PDB
Homo sapiens (human)Protein HUNK1
2D, EH4K5acK8ApmTripolymer131237.42UniProt (by SIFTS) (P62805)
In PDB
Homo sapiens
3CDI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
4waterwater18.0249Chemie (HOH)
Sequence modifications
A, B, C: 44 - 168 (UniProt: O60885)
PDBExternal DatabaseDetails
Gly 40-expression tag
Ser 41-expression tag
His 42-expression tag
Met 43-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight48358.6
Non-Polymers*Number of molecules1
Total formula weight106.1
All*Total formula weight48464.7
*Water molecules are not included.

224004

PDB entries from 2024-08-21

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