8B2N
Potempin A (PotA) from Tannerella forsythia in complex with the catalytic domain of human MMP-12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Macrophage metalloelastase | polymer | 158 | 17484.5 | 2 | UniProt (P39900) Pfam (PF00413) | Homo sapiens (human) | MME,Macrophage elastase,hME,Matrix metalloproteinase-12,MMP-12 |
| 2 | B, D (B, D) | Tannerella forsythia potempin A (PotA) | polymer | 95 | 10759.3 | 2 | UniProt (A0A2A6E6U9) UniProt (by SIFTS) (G8UM88) | Tannerella forsythia | |
| 3 | E, F, G, J, K... (A, C) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | H, I, M, N (A, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence modifications
A, C: 106 - 263 (UniProt: P39900)
| PDB | External Database | Details |
|---|---|---|
| Asp 171 | Phe 171 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56487.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 502.1 | |
| All* | Total formula weight | 56989.6 |
