8B10
Crystal Structure of Shank2-SAM mutant domain - L1800W
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | SH3 and multiple ankyrin repeat domains protein 2 | polymer | 70 | 8184.3 | 6 | UniProt (Q9UPX8) Pfam (PF00536) | Homo sapiens (human) | Shank2,Cortactin-binding protein 1,CortBP1,Proline-rich synapse-associated protein 1 |
| 2 | G (B) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 3 | H (D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | I, J (D, F) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1780 - 1849 (UniProt: Q9UPX8)
| PDB | External Database | Details |
|---|---|---|
| Trp 1800 | Leu 1800 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 49105.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 386.3 | |
| All* | Total formula weight | 49491.8 |
