8AYF

Crystal structure of human Sphingosine-1-phosphate lyase 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Sphingosine-1-phosphate lyase 1	polymer	494	54998.3	2	UniProt (O95470) Pfam (PF00282)	Homo sapiens (human)	S1PL,SP-lyase 1,SPL 1,hSPL,Sphingosine-1-phosphate aldolase
2	C, E (A, B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
3	D, F (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	G, H (A, B)	water	water		18.0	319	Chemie (HOH)

Sequence modifications

A, B: 81 - 568 (UniProt: O95470)

PDB	External Database	Details
His 569	-	expression tag
His 570	-	expression tag
His 571	-	expression tag
His 572	-	expression tag
His 573	-	expression tag
His 574	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	109996.5
Non-Polymers*	Number of molecules	4
	Total formula weight	302.3
All*	Total formula weight	110298.8

*Water molecules are not included.