8AXS
Sialidases and Fucosidases of Akkermansia muciniphila are key for rapid growth on colonic mucin and nutrient sharing amongst mucin-associated human gut microbiota
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Exo-alpha-sialidase | polymer | 578 | 64362.6 | 1 | UniProt (A0A7G6DVF6) Pfam (PF13088) In PDB | Akkermansia muciniphila | |
2 | B | Exo-alpha-sialidase | polymer | 576 | 64278.4 | 1 | UniProt (A0A7G6DVF6) Pfam (PF13088) In PDB | Akkermansia muciniphila | |
3 | A, B | N-acetyl-beta-neuraminic acid | non-polymer | 309.3 | 3 | Chemie (SLB) | |||
4 | A | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
5 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
6 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
7 | A, B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
8 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
9 | B | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID | non-polymer | 291.3 | 1 | Chemie (DAN) | |||
10 | water | water | 18.0 | 1416 | Chemie (HOH) |
Sequence modifications
A: 23 - 595 (UniProt: A0A7G6DVF6)
B: 23 - 595 (UniProt: A0A7G6DVF6)
PDB | External Database | Details |
---|---|---|
Met 22 | - | initiating methionine |
Val 477 | Ala 477 | conflict |
Lys 516 | Arg 516 | conflict |
Ala 598 | - | expression tag |
Ala 599 | - | expression tag |
Ala 600 | - | expression tag |
Ala 601 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 22 | - | initiating methionine |
Val 477 | Ala 477 | conflict |
Lys 516 | Arg 516 | conflict |
Ala 596 | - | expression tag |
Glu 597 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 128641.0 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 1978.6 | |
All* | Total formula weight | 130619.6 |