8AS9
Crystal structure of the talin-KANK1 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | B-cell lymphoma 6 protein | polymer | 137 | 15603.0 | 2 | UniProt (P41182) Pfam (PF00651) In PDB | Homo sapiens (human) | BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51 |
2 | D | KN-motif NCoR1 BBD fusion,Nuclear receptor corepressor 1 | polymer | 51 | 5781.6 | 1 | UniProt (Q8BRZ8) UniProt (O75376) Pfam (PF12075) UniProt (by SIFTS) (Q14678) In PDB | Homo sapiens | N-CoR,N-CoR1 |
3 | C | Talin-1 | polymer | 309 | 32574.7 | 1 | UniProt (P26039) In PDB | Mus musculus (mouse) | |
4 | A, C | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
5 | C | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) |
Sequence modifications
A, B: 6 - 129 (UniProt: P41182)
D: 1 - 31 (UniProt: Q8BRZ8)
D: 36 - 51 (UniProt: O75376)
C: 1359 - 1659 (UniProt: P26039)
PDB | External Database | Details |
---|---|---|
Gly -7 | - | expression tag |
Pro -6 | - | expression tag |
Ser -5 | - | expression tag |
Ser -4 | - | expression tag |
Asp -3 | - | expression tag |
Leu -2 | - | expression tag |
Tyr -1 | - | expression tag |
Leu 0 | - | expression tag |
Arg 1 | - | expression tag |
Pro 2 | - | expression tag |
Gly 3 | - | expression tag |
Gly 4 | - | expression tag |
Gly 5 | - | expression tag |
Gln 8 | Cys 8 | engineered mutation |
Arg 67 | Cys 67 | engineered mutation |
Asn 84 | Cys 84 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 32 | - | linker |
Gly 33 | - | linker |
Gly 34 | - | linker |
Gly 35 | - | linker |
C: 1359 - 1659 (UniProt: P26039)
PDB | External Database | Details |
---|---|---|
Gly 1351 | - | expression tag |
Ile 1352 | - | expression tag |
Asp 1353 | - | expression tag |
Pro 1354 | - | expression tag |
Phe 1355 | - | expression tag |
Thr 1356 | - | expression tag |
Lys 1357 | - | expression tag |
His 1358 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 69562.3 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 476.3 | |
All* | Total formula weight | 70038.6 |