8AS9
Crystal structure of the talin-KANK1 complex
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 134 |
| Details | Domain: {"description":"BTB","evidences":[{"source":"PROSITE-ProRule","id":"PRU00037","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Motif: {"description":"Important for binding to TLN1","evidences":[{"source":"PubMed","id":"27410476","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Motif: {"description":"Nuclear export signal 1 (NES 1)","evidences":[{"source":"PubMed","id":"16968744","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 300 |
| Details | Region: {"description":"Interaction with VCL and F-actin","evidences":[{"source":"PubMed","id":"20610383","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 119 |
| Details | Region: {"description":"Helical bundle R8","evidences":[{"source":"PubMed","id":"23389036","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 72 |
| Details | Region: {"description":"Helical bundle R7B; Interaction with KANK1","evidences":[{"source":"PubMed","id":"27410476","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23389036","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
