8AMS
Complex of human TRIM2 RING domain, UBCH5C, and Ubiquitin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ubiquitin-conjugating enzyme E2 D3 | polymer | 149 | 16955.4 | 2 | UniProt (P61077) Pfam (PF00179) | Homo sapiens (human) | (E3-independent) E2 ubiquitin-conjugating enzyme D3,E2 ubiquitin-conjugating enzyme D3,Ubiquitin carrier protein D3,Ubiquitin-conjugating enzyme E2(17)KB 3,Ubiquitin-conjugating enzyme E2-17 kDa 3,Ubiquitin-protein ligase D3 |
| 2 | C, D (C, D) | Tripartite motif-containing protein 2 | polymer | 153 | 16914.5 | 2 | UniProt (Q9C040) Pfam (PF13445) Pfam (PF00643) | Homo sapiens (human) | E3 ubiquitin-protein ligase TRIM2,RING finger protein 86,RING-type E3 ubiquitin transferase TRIM2 |
| 3 | E (E) | Polyubiquitin-C | polymer | 101 | 11639.2 | 1 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | |
| 4 | F, G, H, I, J... (A, B, C, D) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 5 | L, M, P, Q (C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 6 | R (D) | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL | non-polymer | 370.4 | 1 | Chemie (PE8) | |||
| 7 | T, U, V, W, X (A, B, C, D, E) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 147 (UniProt: P61077)
C, D: 8 - 157 (UniProt: Q9C040)
E: 0 - 76 (UniProt: P0CG48)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Arg 22 | Ser 22 | engineered mutation |
| Ser 85 | Cys 85 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 5 | - | expression tag |
| Ala 6 | - | expression tag |
| Met 7 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -24 | - | initiating methionine |
| Lys -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| Pro -16 | - | expression tag |
| Met -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Tyr -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Ile -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 79379.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1460.9 | |
| All* | Total formula weight | 80839.9 |
