8AH2

Crystal structure of human 14-3-3 zeta fused to the NPM1 peptide including phosphoserine-48

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	14-3-3 protein zeta/delta,Nucleophosmin	polymer	248	27637.1	2	UniProt (P63104) UniProt (P06748) Pfam (PF00244)	Homo sapiens (human)	Protein kinase C inhibitor protein 1,KCIP-1,NPM,Nucleolar phosphoprotein B23,Nucleolar protein NO38,Numatrin
2	C, D (A, C)	water	water		18.0	14	Chemie (HOH)

Sequence modifications

A, C: 1 - 229 (UniProt: P63104)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
His 0	-	expression tag
Ala 58	Ser 58	engineered mutation
Ala 73	Glu 73	engineered mutation
Ala 74	Lys 74	engineered mutation
Ala 75	Lys 75	engineered mutation
Ala 157	Lys 157	engineered mutation
Ala 158	Lys 158	engineered mutation
Ala 159	Glu 159	engineered mutation
Gly 230	-	linker
Gly 231	-	linker
Gly 232	-	linker
Gly 233	-	linker

A, C: 234 - 245 (UniProt: P06748)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55274.1
All*	Total formula weight	55274.1

*Water molecules are not included.