8AG2
Crystal structure of the BPTF bromodomain in complex with BI-7190
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nucleosome-remodeling factor subunit BPTF | polymer | 121 | 14237.1 | 1 | UniProt (Q12830) Pfam (PF00439) | Homo sapiens (human) | Bromodomain and PHD finger-containing transcription factor,Fetal Alz-50 clone 1 protein,Fetal Alzheimer antigen |
| 2 | B (A) | 5-[3-methoxy-4-[1-(4-methylpiperazin-1-yl)cyclopropyl]phenyl]-1,3,4-trimethyl-pyridin-2-one | non-polymer | 381.5 | 1 | Chemie (M1I) | |||
| 3 | C (A) | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14237.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 381.5 | |
| All* | Total formula weight | 14618.7 |
