8AFR
Pim1 in complex with 4-((6-hydroxybenzofuran-3-yl)methyl)benzoic acid and Pimtide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Serine/threonine-protein kinase pim-1 | polymer | 309 | 35356.1 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (human) | |
2 | C | Pimtide | polymer | 14 | 1592.8 | 1 | Synthetic construct | ||
3 | A | 4-((6-hydroxybenzofuran-3-yl)methyl)benzoic acid | non-polymer | 268.3 | 1 | Chemie (M0F) | |||
4 | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A: 1 - 310 (UniProt: P11309)
PDB | External Database | Details |
---|---|---|
Ser 0 | - | expression tag |
- | Gly 47 | deletion |
- | Gly 48 | deletion |
Gly 250 | Arg 250 | engineered mutation |
- | Ser 306 | deletion |
- | Leu 307 | deletion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36949.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 268.3 | |
All* | Total formula weight | 37217.3 |