8AEV
Human acetylcholinesterase in complex with N,N,N-trimethyl-2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazineyl)ethan-1-aminium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetylcholinesterase | polymer | 543 | 59636.3 | 2 | UniProt (P22303) Pfam (PF00135) | Homo sapiens (human) | AChE |
| 2 | C, F (C, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 3 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | E (E) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | branched | 471.4 | 1 | In PDB GlyTouCan (G30207PZ) | |||
| 5 | G (A) | 1-(2-(2-((6-(dihydroxymethyl)-2-phenylpyrimidin-4-yl)methylene)hydrazineyl)-2-oxoethyl)pyridin-1-ium | non-polymer | 366.4 | 1 | Chemie (LWU) | |||
| 6 | H, I, J, K, L... (A, B) | SULFATE ION | non-polymer | 96.1 | 16 | Chemie (SO4) | |||
| 7 | AA, AB, BA, BB, CA... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 31 | Chemie (CL) | |||
| 8 | EA, FA, MB, NB, OB (A, B) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 9 | GA, HA, IA, JA, KA... (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 14 | Chemie (MG) | |||
| 10 | VB, WB (A, B) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119272.6 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2036.9 | |
| Non-Polymers* | Number of molecules | 67 |
| Total formula weight | 3669.8 | |
| All* | Total formula weight | 124979.2 |
