8AEK
Structure of Compound 14 bound to CK2alpha
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Casein kinase II subunit alpha | polymer | 328 | 39031.4 | 1 | UniProt (P68400) Pfam (PF00069) In PDB | Homo sapiens (human) | CK II alpha |
| 2 | A | 2-[5-(trifluoromethyl)-1H-indol-3-yl]ethanenitrile | non-polymer | 224.2 | 1 | Chemie (LVL) | |||
| 3 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | A | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
A: 2 - 329 (UniProt: P68400)
| PDB | External Database | Details |
|---|---|---|
| Ser 21 | Arg 21 | engineered mutation |
| Ala 74 | Lys 74 | engineered mutation |
| Ala 75 | Lys 75 | engineered mutation |
| Ala 76 | Lys 76 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39031.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 908.5 | |
| All* | Total formula weight | 39939.9 |
