8ADM
Ternary complex of 14-3-3 sigma, Usp8pS718 phosphopeptide and small molecule stabilizer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (P) | Ubiquitin carboxyl-terminal hydrolase 8 | polymer | 8 | 1005.0 | 1 | UniProt (P40818) | Homo sapiens | Deubiquitinating enzyme 8,Ubiquitin isopeptidase Y,hUBPy,Ubiquitin thioesterase 8,Ubiquitin-specific-processing protease 8 |
| 3 | C (A) | 1-[2-(4-chloranylphenoxy)-2-methyl-propanoyl]-~{N}-[2-[2-(dimethylamino)ethyldisulfanyl]ethyl]piperidine-4-carboxamide | non-polymer | 488.1 | 1 | Chemie (O6C) | |||
| 4 | D, E (A, P) | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27547.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 488.1 | |
| All* | Total formula weight | 28036.0 |
