8ACI
Structure of ARG-117 Fab in complex with a fragment of complement C2, neutral pH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Complement C2b fragment | polymer | 197 | 20991.4 | 1 | UniProt (P06681) Pfam (PF00084) | Homo sapiens (human) | |
| 2 | B (H) | ARGX-117 Fab heavy chain | polymer | 219 | 23450.1 | 1 | Homo sapiens (Human) | ||
| 3 | C (K) | nanobody specific for kappa light chain of Fab | polymer | 128 | 14204.5 | 1 | Lama glama | ||
| 4 | D (L) | ARGX-117 Fab light chain | polymer | 218 | 23957.6 | 1 | Homo sapiens (Human) | ||
| 5 | E (X) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 6 | F (H) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | G (K) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | H (L) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 9 | I, J, K, L (A, H, K, L) | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 82603.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 367.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 193.7 | |
| All* | Total formula weight | 83164.7 |
