8AAI
Crystal structure of the PDZ tandem of syntenin in complex with fragment E5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Syntenin-1 | polymer | 166 | 18018.7 | 4 | UniProt (O00560) Pfam (PF00595) In PDB | Homo sapiens (human) | Melanoma differentiation-associated protein 9,MDA-9,Pro-TGF-alpha cytoplasmic domain-interacting protein 18,TACIP18,Scaffold protein Pbp1,Syndecan-binding protein 1 |
| 2 | A, B, C, D | (2~{S})-2-[[(2~{S})-3-methyl-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)butanoyl]amino]propanoic acid | non-polymer | 304.3 | 4 | Chemie (LKV) | |||
| 3 | water | water | 18.0 | 188 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 113 - 273 (UniProt: O00560)
| PDB | External Database | Details |
|---|---|---|
| Gly 108 | - | expression tag |
| Ala 109 | - | expression tag |
| Met 110 | - | expression tag |
| Asp 111 | - | expression tag |
| Pro 112 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 72074.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1217.4 | |
| All* | Total formula weight | 73292.1 |
