8A9G
Binary complex of 14-3-3 zeta Glucocorticoid Receptor (GR) pT524 peptide stabilised by (R)-para chloropyrrolidone1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 14-3-3 protein zeta/delta | polymer | 235 | 26720.2 | 2 | UniProt (P63104) Pfam (PF00244) | Homo sapiens (human) | Protein kinase C inhibitor protein 1,KCIP-1 |
| 2 | C, D (C, D) | Glucocorticoid receptor | polymer | 13 | 1459.6 | 2 | UniProt (P04150) | Homo sapiens | GR,Nuclear receptor subfamily 3 group C member 1 |
| 3 | E, G (A, B) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 2 | Chemie (BTB) PubChem (81462) | |||
| 4 | F, I (A, B) | 5-[(2~{R})-3-(4-chlorophenyl)carbonyl-2-(4-nitrophenyl)-4-oxidanyl-5-oxidanylidene-2~{H}-pyrrol-1-yl]-2-oxidanyl-benzoic acid | non-polymer | 494.8 | 2 | Chemie (QJK) | |||
| 5 | H (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 6 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 283 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 230 (UniProt: P63104)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56359.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1432.5 | |
| All* | Total formula weight | 57792.2 |
