8A17

Human PTPRM domains FN3-4, in spacegroup P3221

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Receptor-type tyrosine-protein phosphatase mu	polymer	258	28947.3	4	UniProt (P28827) Pfam (PF00041) Pfam (PF23144)	Homo sapiens (human)	Protein-tyrosine phosphatase mu,R-PTP-mu
2	E, G, I (E, G, I)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	3	In PDB GlyTouCan (G32152BH)
3	F (F)	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	1	In PDB GlyTouCan (G00395TQ)
4	H, J (H, J)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	2	In PDB GlyTouCan (G21290RB)
5	K (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A, B, C, D: 478 - 723 (UniProt: P28827)

PDB	External Database	Details
Glu 475	-	cloning artifact
Thr 476	-	cloning artifact
Gly 477	-	cloning artifact
Gly 724	-	expression tag
Thr 725	-	expression tag
Lys 726	-	expression tag
His 727	-	expression tag
His 728	-	expression tag
His 729	-	expression tag
His 730	-	expression tag
His 731	-	expression tag
His 732	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	115789.1
Branched	Number of molecules	6
	Total formula weight	4234.0
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	120244.3

*Water molecules are not included.