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8A0G

Human deoxyhypusine synthase with trapped transition state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Deoxyhypusine synthasepolymer37141258.72UniProt (P49366)
Pfam (PF01916)
Homo sapiens (human)DHS
2C
(A)
1,3-DIAMINOPROPANEnon-polymer74.11Chemie (13D)
3D
(A)
(4R)-2-METHYLPENTANE-2,4-DIOLnon-polymer118.21Chemie (MRD)
4E, G
(A, B)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.42Chemie (NAD)
5F
(B)
SPERMIDINEnon-polymer145.21Chemie (SPD)
6H, I
(A, B)
waterwater18.0305Chemie (HOH)
Sequence modifications
A, B: 1 - 369 (UniProt: P49366)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight82517.5
Non-Polymers*Number of molecules5
Total formula weight1664.4
All*Total formula weight84181.9
*Water molecules are not included.

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PDB entries from 2024-11-06

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