7ZY6
Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HUMAN PROTO-ONCOGENE C-KIT | polymer | 327 | 37178.0 | 1 | Pfam (PF07714) UniProt (by SIFTS) (P10721) | Homo sapiens | |
| 2 | B (A) | 5-imidazo[1,2-a]pyridin-3-yl-~{N}-[(1~{R})-1-(6-pyrrolidin-1-ylpyridin-3-yl)ethyl]pyridin-3-amine | non-polymer | 384.5 | 1 | Chemie (KCI) | |||
| 3 | C (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37178.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 384.5 | |
| All* | Total formula weight | 37562.4 |
