7ZXE
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | M | Transcription initiation factor IIB | polymer | 316 | 34877.9 | 1 | UniProt (Q00403) Pfam (PF08271) Pfam (PF00382) In PDB | Homo sapiens (human) | General transcription factor TFIIB,S300-II |
| 2 | N | Non-template strand | polymer | 96 | 29969.1 | 1 | GenBank (8452475) | Homo sapiens | |
| 3 | O | TATA-box-binding protein | polymer | 339 | 37729.9 | 1 | UniProt (P20226) Pfam (PF00352) In PDB | Homo sapiens (human) | TATA sequence-binding protein,TATA-binding factor,TATA-box factor,Transcription initiation factor TFIID TBP subunit |
| 4 | T | Template strand | polymer | 96 | 29261.7 | 1 | GenBank (8452475) | Homo sapiens | |
| 5 | U | Transcription initiation factor IIA subunit 1 | polymer | 376 | 41544.6 | 1 | UniProt (P52655) Pfam (PF03153) In PDB | Homo sapiens (human) | General transcription factor IIA subunit 1,TFIIAL,Transcription initiation factor TFIIA 42 kDa subunit,TFIIA-42 |
| 6 | V | Transcription initiation factor IIA subunit 2 | polymer | 109 | 12469.1 | 1 | UniProt (P52657) Pfam (PF02268) Pfam (PF02751) In PDB | Homo sapiens (human) | General transcription factor IIA subunit 2,TFIIA p12 subunit,TFIIA-12,TFIIAS,Transcription initiation factor IIA gamma chain,TFIIA-gamma |
| 7 | a | snRNA-activating protein complex subunit 1 | polymer | 368 | 43074.5 | 1 | UniProt (Q16533) Pfam (PF09808) In PDB | Homo sapiens (human) | SNAPc subunit 1,Proximal sequence element-binding transcription factor subunit gamma,PSE-binding factor subunit gamma,PTF subunit gamma,Small nuclear RNA-activating complex polypeptide 1,snRNA-activating protein complex 43 kDa subunit,SNAPc 43 kDa subunit |
| 8 | b | snRNA-activating protein complex subunit 3 | polymer | 411 | 46812.6 | 1 | UniProt (Q92966) Pfam (PF12251) In PDB | Homo sapiens (human) | SNAPc subunit 3,Proximal sequence element-binding transcription factor subunit beta,PSE-binding factor subunit beta,PTF subunit beta,Small nuclear RNA-activating complex polypeptide 3,snRNA-activating protein complex 50 kDa subunit,SNAPc 50 kDa subunit |
| 9 | c | snRNA-activating protein complex subunit 4 | polymer | 1469 | 159645.2 | 1 | UniProt (Q5SXM2) Pfam (PF13921) In PDB | Homo sapiens (human) | SNAPc subunit 4,Proximal sequence element-binding transcription factor subunit alpha,PSE-binding factor subunit alpha,PTF subunit alpha,snRNA-activating protein complex 190 kDa subunit,SNAPc 190 kDa subunit |
| 10 | d | snRNA-activating protein complex subunit 5 | polymer | 98 | 11343.4 | 1 | UniProt (O75971) Pfam (PF15497) In PDB | Homo sapiens (human) | SNAPc subunit 5,Small nuclear RNA-activating complex polypeptide 5,snRNA-activating protein complex 19 kDa subunit,SNAPc 19 kDa subunit |
| 11 | b | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 446728.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 446858.9 |
