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7ZXE

Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(M)
Transcription initiation factor IIBpolymer31634877.91UniProt (Q00403)
Pfam (PF08271)
Pfam (PF00382)
Homo sapiens (human)General transcription factor TFIIB,S300-II
2B
(N)
Non-template strandpolymer9629969.11GenBank (8452475)Homo sapiens
3C
(O)
TATA-box-binding proteinpolymer33937729.91UniProt (P20226)
Pfam (PF00352)
Homo sapiens (human)TATA sequence-binding protein,TATA-binding factor,TATA-box factor,Transcription initiation factor TFIID TBP subunit
4D
(T)
Template strandpolymer9629261.71GenBank (8452475)Homo sapiens
5E
(U)
Transcription initiation factor IIA subunit 1polymer37641544.61UniProt (P52655)
Pfam (PF03153)
Homo sapiens (human)General transcription factor IIA subunit 1,TFIIAL,Transcription initiation factor TFIIA 42 kDa subunit,TFIIA-42
6F
(V)
Transcription initiation factor IIA subunit 2polymer10912469.11UniProt (P52657)
Pfam (PF02268)
Pfam (PF02751)
Homo sapiens (human)General transcription factor IIA subunit 2,TFIIA p12 subunit,TFIIA-12,TFIIAS,Transcription initiation factor IIA gamma chain,TFIIA-gamma
7G
(a)
snRNA-activating protein complex subunit 1polymer36843074.51UniProt (Q16533)
Pfam (PF09808)
Homo sapiens (human)SNAPc subunit 1,Proximal sequence element-binding transcription factor subunit gamma,PSE-binding factor subunit gamma,PTF subunit gamma,Small nuclear RNA-activating complex polypeptide 1,snRNA-activating protein complex 43 kDa subunit,SNAPc 43 kDa subunit
8H
(b)
snRNA-activating protein complex subunit 3polymer41146812.61UniProt (Q92966)
Pfam (PF12251)
Homo sapiens (human)SNAPc subunit 3,Proximal sequence element-binding transcription factor subunit beta,PSE-binding factor subunit beta,PTF subunit beta,Small nuclear RNA-activating complex polypeptide 3,snRNA-activating protein complex 50 kDa subunit,SNAPc 50 kDa subunit
9I
(c)
snRNA-activating protein complex subunit 4polymer1469159645.21UniProt (Q5SXM2)
Pfam (PF13921)
Homo sapiens (human)SNAPc subunit 4,Proximal sequence element-binding transcription factor subunit alpha,PSE-binding factor subunit alpha,PTF subunit alpha,snRNA-activating protein complex 190 kDa subunit,SNAPc 190 kDa subunit
10J
(d)
snRNA-activating protein complex subunit 5polymer9811343.41UniProt (O75971)
Pfam (PF15497)
Homo sapiens (human)SNAPc subunit 5,Small nuclear RNA-activating complex polypeptide 5,snRNA-activating protein complex 19 kDa subunit,SNAPc 19 kDa subunit
11K, L
(b)
ZINC IONnon-polymer65.42Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight446728.1
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight446858.9
*Water molecules are not included.

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PDB entries from 2025-12-03

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