7ZUN
Crystal structure of PIM1 in complex with a Pyrrolo-Pyrazinone compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Isoform 2 of Serine/threonine-protein kinase pim-1 | polymer | 314 | 35835.7 | 1 | UniProt (P11309-2) Pfam (PF00069) UniProt (by SIFTS) (P11309) In PDB | Homo sapiens (human) | |
| 2 | A | (4~{S})-4-(2-azanylethyl)-6-phenyl-7-[3-(trifluoromethyloxy)phenyl]-3,4-dihydropyrrolo[1,2-a]pyrazin-1-ol | non-polymer | 415.4 | 1 | Chemie (JYO) | |||
| 3 | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A: 2 - 313 (UniProt: P11309-2)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Pro 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35835.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 415.4 | |
| All* | Total formula weight | 36251.1 |
