7ZU1
Crystal structure of mutant AR-LBD (V758A) bound to dihydrotestosterone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 249 | 29018.0 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| 2 | B (A) | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 1 | Chemie (DHT) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (A) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
| 6 | F (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 7 | G (A) | LITHIUM ION | non-polymer | 6.9 | 1 | Chemie (LI) | |||
| 8 | H (A) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
A: 672 - 920 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Ala 758 | Val 758 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29018.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 708.9 | |
| All* | Total formula weight | 29726.9 |
