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7ZRY

Structure of the 2a splicing variant of the full-length human LSD1 bound to CoREST (delta305)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform of Lysine-specific histone demethylase 1Apolymer87294820.21Pfam (PF04433)
Pfam (PF01593)
UniProt (by SIFTS) (O60341)
Homo sapiens (human)BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2,[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A
2B
(B)
REST corepressor 1polymer17820244.81UniProt (Q9UKL0)
Pfam (PF20878)
Pfam (PF00249)
Homo sapiens (human)Protein CoREST
3C
(A)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight115065.0
Non-Polymers*Number of molecules1
Total formula weight785.5
All*Total formula weight115850.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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