7ZRB
Crystal structure of Beta-catenin Armadillo repeats domain in complex with the inhibitor RS6452
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Catenin beta-1 | polymer | 539 | 58978.3 | 2 | UniProt (A0A2R8Y804) Pfam (PF00514) UniProt (by SIFTS) (P35222) | Homo sapiens (human) | |
| 2 | C (A) | 4-bromanyl-~{N}-(3-pyridin-2-ylphenyl)benzenesulfonamide | non-polymer | 389.3 | 1 | Chemie (JKI) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A, B: 133 - 664 (UniProt: A0A2R8Y804)
| PDB | External Database | Details |
|---|---|---|
| Glu 126 | - | expression tag |
| Asn 127 | - | expression tag |
| Leu 128 | - | expression tag |
| Tyr 129 | - | expression tag |
| Phe 130 | - | expression tag |
| Gln 131 | - | expression tag |
| Ser 132 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 117956.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 389.3 | |
| All* | Total formula weight | 118345.9 |
