7ZP2
Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with BDA-04
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Aspartate carbamoyltransferase | polymer | 349 | 40350.8 | 6 | UniProt (A0A5K1K910) Pfam (PF02729) Pfam (PF00185) In PDB | Plasmodium falciparum 3D7 | |
| 2 | A | tert-butyl N-[5-phenyl-3-(2-phenylethylcarbamoyl)thiophen-2-yl]carbamate | non-polymer | 422.5 | 1 | Chemie (EJG) | |||
| 3 | B, C, D | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | B, F | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 37 - 375 (UniProt: A0A5K1K910)
| PDB | External Database | Details |
|---|---|---|
| Ser 376 | - | expression tag |
| Ala 377 | - | expression tag |
| Trp 378 | - | expression tag |
| Ser 379 | - | expression tag |
| His 380 | - | expression tag |
| Pro 381 | - | expression tag |
| Gln 382 | - | expression tag |
| Phe 383 | - | expression tag |
| Glu 384 | - | expression tag |
| Lys 385 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 242104.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 852.8 | |
| All* | Total formula weight | 242957.3 |
