7ZN7

Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and rat STAT2 CCD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA damage-binding protein 1	polymer	840	93671.5	1	UniProt (Q16531) Pfam (PF10433) Pfam (PF03178)	Homo sapiens (human)	DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe
2	B (B)	B27a	polymer	659	76341.9	1	UniProt (K7Y9Z1) Pfam (PF05999)	Murid betaherpesvirus 8	E27a
3	C (D)	Signal transducer and activator of transcription	polymer	845	97173.0	1	UniProt (Q5XI26) Pfam (PF02865) Pfam (PF01017) Pfam (PF02864) Pfam (PF21354) Pfam (PF00017) Pfam (PF12188)	Rattus norvegicus (Norway rat)
4	D (B)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 1 - 699 (UniProt: Q16531)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag

A: 706 - 1140 (UniProt: Q16531)

PDB	External Database	Details
Gly 700	-	linker
Asn 701	-	linker
Gly 702	-	linker
Asn 703	-	linker
Ser 704	-	linker
Gly 705	-	linker

B: 1 - 656 (UniProt: K7Y9Z1)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag

D: 1 - 842 (UniProt: Q5XI26)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	267186.3
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	267251.7

*Water molecules are not included.