7ZN7

Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and rat STAT2 CCD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0005634	cellular_component	nucleus
D	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006355	biological_process	regulation of DNA-templated transcription
D	0006357	biological_process	regulation of transcription by RNA polymerase II
D	0007165	biological_process	signal transduction
D	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
D	0008150	biological_process	biological_process
D	0042802	molecular_function	identical protein binding
D	0044389	molecular_function	ubiquitin-like protein ligase binding
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0051607	biological_process	defense response to virus
D	0060337	biological_process	type I interferon-mediated signaling pathway
D	0060339	biological_process	negative regulation of type I interferon-mediated signaling pathway
D	0070721	cellular_component	ISGF3 complex
D	0090140	biological_process	regulation of mitochondrial fission

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	25
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGNGNSGEIQkLhirtvplye.........SPRK

Chain	Residue	Details
A	ILE699-LYS723

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q9ESW0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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