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7ZMO

Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G3-052

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
ATP-dependent DNA helicase Q5polymer44549537.22UniProt (O94762)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF16124)
Homo sapiens (human)DNA helicase,RecQ-like type 5,RecQ5,RecQ protein-like 5
2C, D
(K, C)
Gluebody G3-052polymer12713695.12Lama glama
3E, G
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
4F, H
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
5I, J
(A, K)
waterwater18.04Chemie (HOH)
Sequence modifications
A, B: 11 - 453 (UniProt: O94762)
PDBExternal DatabaseDetails
Ser 9-expression tag
Met 10-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight126464.5
Non-Polymers*Number of molecules4
Total formula weight322.9
All*Total formula weight126787.4
*Water molecules are not included.

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PDB entries from 2025-07-02

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