7ZM2
Crystal structure of HsaD from Mycobacterium tuberculosis in complex with Cyclophostin-like inhibitor CyC8b
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | polymer | 299 | 32986.6 | 2 | UniProt (P9WNH5) Pfam (PF00561) In PDB | Mycobacterium tuberculosis H37Rv | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase,HOPDA hydrolase,Meta-cleavage product hydrolase,MCP hydrolase |
2 | A, B | methoxy-[(3~{R})-3-[(2~{R})-1-methoxy-1,3-bis(oxidanylidene)butan-2-yl]pentadecyl]phosphinic acid | non-polymer | 420.5 | 2 | Chemie (9SW) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
4 | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 291 (UniProt: P9WNH5)
PDB | External Database | Details |
---|---|---|
Lys 292 | - | expression tag |
Leu 293 | - | expression tag |
His 294 | - | expression tag |
His 295 | - | expression tag |
His 296 | - | expression tag |
His 297 | - | expression tag |
His 298 | - | expression tag |
His 299 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 65973.2 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1321.4 | |
All* | Total formula weight | 67294.5 |