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7ZKS

SRPK1 IN COMPLEX WITH INHIBITOR

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
SRSF protein kinase 1polymer38744085.41UniProt (Q96SB4)
Pfam (PF00069)
Homo sapiens (human)SFRS protein kinase 1,Serine/arginine-rich protein-specific kinase 1,SR-protein-specific kinase 1
2B
(A)
N-[3-[[[2-(6-chloranyl-5-fluoranyl-1H-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]-N-methyl-methanesulfonamidenon-polymer461.91Chemie (IXQ)
3C
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4D
(A)
waterwater18.0165Chemie (HOH)
Sequence modifications
A: 50 - 474 (UniProt: Q96SB4)
A: 475 - 655 (UniProt: Q96SB4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight44085.4
Non-Polymers*Number of molecules2
Total formula weight497.4
All*Total formula weight44582.8
*Water molecules are not included.

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PDB entries from 2025-06-25

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