7ZKL
X-ray structure of the complex between human alpha thrombin and a pseudo-cyclic thrombin binding aptamer (TBA-NNp/DDp) - Crystal form alpha
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Thrombin light chain | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (H) | Thrombin heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (A) | TBA-NNp/DDp | polymer | 15 | 4743.1 | 1 | synthetic construct | ||
| 4 | D (H) | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 1 | Chemie (0G6) | |||
| 5 | E (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F (H) | (2S)-2-hydroxybutanedioic acid | non-polymer | 134.1 | 1 | Chemie (LMR) | |||
| 7 | G (A) | 3-[13-methyl-5,7,12,14-tetrakis(oxidanylidene)-6,13-diazatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(15),2,4(16),8,10-pentaen-6-yl]propyl 3-[5,7,12,14-tetrakis(oxidanylidene)-13-(3-oxidanylpropyl)-6,13-diazatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1,3,8(16),9,11(15)-pentaen-6-yl]propyl hydrogen phosphate | non-polymer | 1044.7 | 1 | Chemie (JL0) | |||
| 8 | H (A) | 3-[5-[3-bis(oxidanyl)phosphanyloxypropoxy]naphthalen-1-yl]oxypropyl 3-(5-oxidanylnaphthalen-1-yl)oxypropyl hydrogen phosphate | non-polymer | 620.5 | 1 | Chemie (JKR) | |||
| 9 | I (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 10 | J, K, L (L, H, A) | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 38619.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2315.4 | |
| All* | Total formula weight | 40935.2 |
