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7ZJU

Structure of human USPL1 in covalent complex with SUMO3-2Br probe

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
SUMO-specific isopeptidase USPL1polymer28733203.12UniProt (Q5W0Q7)
Pfam (PF15499)
Homo sapiens (human)
2B, D
(B, D)
Small ubiquitin-related modifier 3polymer9010351.62UniProt (P55854)
Pfam (PF11976)
Homo sapiens (human)SUMO-3,SMT3 homolog 1,SUMO-2,Ubiquitin-like protein SMT3A,Smt3A
3E, J
(A, C)
ZINC IONnon-polymer65.42Chemie (ZN)
4F, K, O
(A, C, D)
GLYCEROLnon-polymer92.13Chemie (GOL)
5G, L
(A, C)
2-bromanylethanaminenon-polymer124.02Chemie (OXU)
6H, M
(A, C)
CHLORIDE IONnon-polymer35.52Chemie (CL)
7I, N
(A, C)
CALCIUM IONnon-polymer40.12Chemie (CA)
8P, Q, R, S
(A, B, C, D)
waterwater18.0331Chemie (HOH)
Sequence modifications
A, C: 218 - 502 (UniProt: Q5W0Q7)
PDBExternal DatabaseDetails
Gly 216-expression tag
Pro 217-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight87109.3
Non-Polymers*Number of molecules11
Total formula weight806.1
All*Total formula weight87915.4
*Water molecules are not included.

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PDB entries from 2025-07-16

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