7ZJS
Structural basis of centromeric cohesion protection by SGO1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Cohesin subunit SA-2 | polymer | 1231 | 141502.1 | 2 | UniProt (Q8N3U4) Pfam (PF08514) Pfam (PF21581) | Homo sapiens (human) | SCC3 homolog 2,Stromal antigen 2 |
| 2 | B, D (B, D) | Double-strand-break repair protein rad21 homolog | polymer | 631 | 71772.4 | 2 | UniProt (O60216) Pfam (PF04825) Pfam (PF04824) | Homo sapiens (human) | hHR21,Nuclear matrix protein 1,NXP-1,SCC1 homolog |
| 3 | E, F (E, F) | Shugoshin 1 | polymer | 11 | 1315.3 | 2 | UniProt (Q5FBB7) | Homo sapiens | Serologically defined breast cancer antigen NY-BR-85,Shugoshin-like 1 |
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 1231 (UniProt: Q8N3U4)
| PDB | External Database | Details |
|---|---|---|
| Arg 545 | Lys 545 | conflict |
| Lys 546 | Arg 546 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 429179.5 | |
| All* | Total formula weight | 429179.5 |
