7ZJS

Structural basis of centromeric cohesion protection by SGO1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000775	cellular_component	chromosome, centromeric region
A	0000785	cellular_component	chromatin
A	0001650	cellular_component	fibrillar center
A	0003682	molecular_function	chromatin binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0005730	cellular_component	nucleolus
A	0005829	cellular_component	cytosol
A	0007059	biological_process	chromosome segregation
A	0007062	biological_process	sister chromatid cohesion
A	0008278	cellular_component	cohesin complex
A	0016020	cellular_component	membrane
A	0016363	cellular_component	nuclear matrix
A	0034087	biological_process	establishment of mitotic sister chromatid cohesion
A	0051301	biological_process	cell division
A	0051321	biological_process	meiotic cell cycle
A	0090307	biological_process	mitotic spindle assembly
A	0097431	cellular_component	mitotic spindle pole
B	0000775	cellular_component	chromosome, centromeric region
B	0000785	cellular_component	chromatin
B	0000794	cellular_component	condensed nuclear chromosome
B	0000922	cellular_component	spindle pole
B	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
B	0001666	biological_process	response to hypoxia
B	0003677	molecular_function	DNA binding
B	0003682	molecular_function	chromatin binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005694	cellular_component	chromosome
B	0005829	cellular_component	cytosol
B	0006281	biological_process	DNA repair
B	0006302	biological_process	double-strand break repair
B	0006310	biological_process	DNA recombination
B	0006351	biological_process	DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0006915	biological_process	apoptotic process
B	0006974	biological_process	DNA damage response
B	0007059	biological_process	chromosome segregation
B	0007062	biological_process	sister chromatid cohesion
B	0007131	biological_process	reciprocal meiotic recombination
B	0008278	cellular_component	cohesin complex
B	0010628	biological_process	positive regulation of gene expression
B	0010629	biological_process	negative regulation of gene expression
B	0010972	biological_process	negative regulation of G2/M transition of mitotic cell cycle
B	0016020	cellular_component	membrane
B	0016363	cellular_component	nuclear matrix
B	0030893	cellular_component	meiotic cohesin complex
B	0032691	biological_process	negative regulation of interleukin-1 beta production
B	0032720	biological_process	negative regulation of tumor necrosis factor production
B	0032733	biological_process	positive regulation of interleukin-10 production
B	0034087	biological_process	establishment of mitotic sister chromatid cohesion
B	0034089	biological_process	establishment of meiotic sister chromatid cohesion
B	0034351	biological_process	negative regulation of glial cell apoptotic process
B	0043524	biological_process	negative regulation of neuron apoptotic process
B	0045841	biological_process	negative regulation of mitotic metaphase/anaphase transition
B	0045876	biological_process	positive regulation of sister chromatid cohesion
B	0051301	biological_process	cell division
B	0071168	biological_process	protein localization to chromatin
B	0106222	molecular_function	lncRNA binding
B	0140297	molecular_function	DNA-binding transcription factor binding
B	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
C	0000775	cellular_component	chromosome, centromeric region
C	0000785	cellular_component	chromatin
C	0001650	cellular_component	fibrillar center
C	0003682	molecular_function	chromatin binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005694	cellular_component	chromosome
C	0005730	cellular_component	nucleolus
C	0005829	cellular_component	cytosol
C	0007059	biological_process	chromosome segregation
C	0007062	biological_process	sister chromatid cohesion
C	0008278	cellular_component	cohesin complex
C	0016020	cellular_component	membrane
C	0016363	cellular_component	nuclear matrix
C	0034087	biological_process	establishment of mitotic sister chromatid cohesion
C	0051301	biological_process	cell division
C	0051321	biological_process	meiotic cell cycle
C	0090307	biological_process	mitotic spindle assembly
C	0097431	cellular_component	mitotic spindle pole
D	0000775	cellular_component	chromosome, centromeric region
D	0000785	cellular_component	chromatin
D	0000794	cellular_component	condensed nuclear chromosome
D	0000922	cellular_component	spindle pole
D	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
D	0001666	biological_process	response to hypoxia
D	0003677	molecular_function	DNA binding
D	0003682	molecular_function	chromatin binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005694	cellular_component	chromosome
D	0005829	cellular_component	cytosol
D	0006281	biological_process	DNA repair
D	0006302	biological_process	double-strand break repair
D	0006310	biological_process	DNA recombination
D	0006351	biological_process	DNA-templated transcription
D	0006357	biological_process	regulation of transcription by RNA polymerase II
D	0006915	biological_process	apoptotic process
D	0006974	biological_process	DNA damage response
D	0007059	biological_process	chromosome segregation
D	0007062	biological_process	sister chromatid cohesion
D	0007131	biological_process	reciprocal meiotic recombination
D	0008278	cellular_component	cohesin complex
D	0010628	biological_process	positive regulation of gene expression
D	0010629	biological_process	negative regulation of gene expression
D	0010972	biological_process	negative regulation of G2/M transition of mitotic cell cycle
D	0016020	cellular_component	membrane
D	0016363	cellular_component	nuclear matrix
D	0030893	cellular_component	meiotic cohesin complex
D	0032691	biological_process	negative regulation of interleukin-1 beta production
D	0032720	biological_process	negative regulation of tumor necrosis factor production
D	0032733	biological_process	positive regulation of interleukin-10 production
D	0034087	biological_process	establishment of mitotic sister chromatid cohesion
D	0034089	biological_process	establishment of meiotic sister chromatid cohesion
D	0034351	biological_process	negative regulation of glial cell apoptotic process
D	0043524	biological_process	negative regulation of neuron apoptotic process
D	0045841	biological_process	negative regulation of mitotic metaphase/anaphase transition
D	0045876	biological_process	positive regulation of sister chromatid cohesion
D	0051301	biological_process	cell division
D	0071168	biological_process	protein localization to chromatin
D	0106222	molecular_function	lncRNA binding
D	0140297	molecular_function	DNA-binding transcription factor binding
D	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	170
Details	Domain: {"description":"SCD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00750","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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