7ZGJ

Trypanosoma brucei gambiense ISG65 in complex with human complement component C3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Complement C3 beta chain	polymer	645	71393.3	1	UniProt (P01024) Pfam (PF17790) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) In PDB	Homo sapiens (human)
2	B	Complement C3	polymer	992	113169.9	1	UniProt (P01024) Pfam (PF21308) Pfam (PF07677) Pfam (PF01759) Pfam (PF01821) Pfam (PF00207) Pfam (PF21406) Pfam (PF07678) In PDB	Homo sapiens (human)	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
3	C	65 kDa invariant surface glycoprotein, putative	polymer	367	40823.5	1	UniProt (C9ZJ67) Pfam (PF11727) In PDB	Trypanosoma brucei gambiense

Sequence modifications

C: 17 - 363 (UniProt: C9ZJ67)

PDB	External Database	Details
Met -3	-	initiating methionine
Gly -2	-	expression tag
Ser -1	-	expression tag
Ser 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
Ser 7	-	expression tag
Ser 8	-	expression tag
Gly 9	-	expression tag
Leu 10	-	expression tag
Val 11	-	expression tag
Pro 12	-	expression tag
Arg 13	-	expression tag
Gly 14	-	expression tag
Ser 15	-	expression tag
His 16	-	expression tag
Met 17	Val 17	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	225386.7
All*	Total formula weight	225386.7

*Water molecules are not included.